Jack Faller

Professor of Chemistry, Inorganic & Organic Chemistry
E-mail: jack.faller@yale.edu
Web site: http://jaxindy.chem.yale.edu

Biographical Sketch

BS summa cum laude University of Louisville, 1963
M.S. University of Louisville, 1964
Ph.D. Massachusetts Institute of Technology, 1967
Joined Yale faculty 1966
A.P. Sloan Fellow, 1970
Guggenheim Fellow, 1972

Research Description

The goal of our research is to gain an understanding of how transition metal complexes and organometallic compounds can be used to control the stereochemistry of organic reactions.

Current topics of interest are: asymmetric catalysis; asymmetric catalysis using racemic catalysts and chiral inhibitors (chiral poisoning) or chiral accelerants; X-ray crystallography; nmr spectroscopy; fluxional and stereochemically nonrigid molecules (particularly 16-electron species), nmr of paramagnetic molecules; stereochemistry of organometallics; mechanisms of inorganic and organometallic reactions; electronic control of stereochemistry in reactions of organometallics; organometallic reagents for organic synthesis; pseudoenantiomeric complexes; kinetic resolutions, spontaneous resolution, asymmetric transformations, quasi-racemates, and transmetallations using organogermanium compounds.

Selected References

Chiral Poisoning and Asymmetric Activation, J. W. Faller, J. Parr, A. Lavoie, Chem. Rev. 2003, 103, 3345-3367.
Kinetic Resolution and Unusual Regioselectivity in Palladium-Catalyzed Allylic Alkylations with a Chiral P,S ligand, J.W. Faller, J. C. Wilt, J. Parr, Org. Lett. 2004 6, 1301-1304.
Novel Binding Modes and Hemilability in Atropisomeric Phosphino-amino Palladium Complexes, J.W. Faller, N. Sarantopoulos, Organometallics, 2004, 23, 2008-2014.
Retention of Configuration and Regiochemistry in Allylic Alkylations via the Memory Effect, J. W. Faller, N. Sarantopoulos, Organometallics, 2004, 23, 2179-2185.
Alkynyl germatranes as alternative reagents for the preparation of biarylethynes, J.W. Faller, R. G. Kultyshev, J. Parr, Tetrahedron Lett. 2003, 44, 451-453.
Enantioselective routes to both enantiomers of aryl alcohols with a single catalyst antipode: Ru and Os transfer hydrogenation catalysts, J. W. Faller, A. Lavoie, Org. Lett. 2001, 3, 3703-3706.
An Application of Electronic Asymmetry to Highly Enantioselective Catalytic Diels-Alder Reactions, J. W. Faller, B. J. Grimmond, and D. D=Allessi, J. Am. Chem. Soc., 2001, 123, 2575-2529.

Last modified: July 10, 2005 (kp)

Jack Faller
Professor of Chemistry, Inorganic & Organic Chemistry