Department of Chemistry
Yale University
225 Prospect Street
PO Box 208107
New Haven CT 06520 8107
203 432 3915

Richard Baxter

Assistant Professor of Chemistry
Member of Yale faculty since 2010

E-mail: richard.baxter@yale.edu
Web site:

Research The Baxter lab is interested in the innate immune response of
arthropods, especially the complement-like system in Anopheles gambiae,
host-pathogen interactions, and the development of new chemical entities
for the control of vector-borne disease. Our primary research tools are
biophysical methods, including macromolecular crystallography and
small-angle x-ray scattering, biochemistry and chemical biology. Our
approach is multi-disciplinary and interfaces with both cross-campus and
international collaborators studying vector biology and infectious disease.

Education
B.Sc. (Hons.) Australian National University, 1998
Ph.D. University of Chicago, 2004

Honors
Boomerang Award, Australian National University, 2009
NIAID Research Scholar (K22) Award, 2010

Recent Publications
R.H.G. Baxter, C.-I Chang, Y. Chelliah, S. Blandin, E.A. Levashina, & J. Deisenhofer. Structural basis for conserved complement factor-like function in the antimalarial protein TEP1. Proc. Nat. Acad. Sci. USA 2007, 104, 11615-20.

M. Fraiture, R.H.G. Baxter, S. Steinert, Y. Chelliah, C. Frolet, W. Quispe-Tintaya, J.A. Hoffmann, S.A. Blandin, & E.A. Levashina. Two mosquito LRR proteins function as complement control factors in the TEP1-mediated killing of Plasmodium. Cell Host Microbe 2009, 5, 273-84.

R.H.G. Baxter, S. Steinert, Y. Chelliah, G. Volohonsky, E.A. Levashina, & J. Deisenhofer. A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae. Proc. Nat. Acad. Sci. USA 2010, in press.